4. Marine natural products

Currently, marine sources provide the most interesting new natural products with novel carbon skeletons and new unprecedented bioactivities, including totally unexpected modes of action. Being based in Kiel, directly situated at the coast of the Baltic Sea and being closely linked to a very strong marine research centre, our future research will also be focused on marine organisms and their natural products chemistry. As current research by other groups in marine natural products is usually only centred at finding new metabolites, our approach of systematic comparative analyses of phylogenetically related groups of organisms will therefore constitute a novel approach in marine natural products chemistry.

 

Reviews

Zidorn, C., 2016. Secondary metabolites of seagrasses (Alismatales and Potamogetonales; Alismatidae): Chemical diversity, bioactivity, and ecological function. Phytochemistry 124, 5-28. doi:10.1016/j.phytochem.2016.02.004

Heglmeier, A., Zidorn, C., 2010. Secondary metabolites of Posidonia oceanica (Posidoniaceae). Biochem. Syst. Ecol. 38, 964-970. doi:10.1016/j.bse.2010.07.001

 

Original publications

Giordano, G., Carbone, M., Ciavatta, M.L., Silvano, E., Gavagnin, M., Garson, M.J., Cheney, K.L., Mudianta W., Russo, G.F., Villani, G., Magliozzi, L., Polese, G., Zidorn, C., Cutignano, A., Fontana, A., Ghiselin, M.T., Mollo, E. (accepted). Volatile secondary metabolites as aposematic olfactory signals and defensive weapons in aquatic environments. Proc. Nat. Acad. Sci. U.S.A. (published online 13.03.2017). doi:10.1073/pnas.1614655114