2. Chemophenetics

In the (macro-) molecular phylogenetics era, chemophenetic studies provide phenetic characters to define previously not recognized and morphologically not definable clades. Moreover, chemophenetic studies provide a rational approach to search for new sources of rare natural products, which are of interest in e.g. the fields of medicine or agriculture. Also the search for new natural products can be rationalized using a chemophenetic approach.

 

Editorial

Zidorn, C., 2019. Plant chemophenetics − a new term for plant chemosystematics/plant chemotaxonomy in the macro-molecular era. Phytochemistry 163, 147-148. doi:10.1016/j.phytochem.2019.02.013

Plant chemosystematic or chemotaxonomic studies based purely on the profiles of small molecules have become obsolete as tools to study phylogenetic relationships of higher plants due to the advent of the much more powerful (macro-) molecular techniques and new methods of data analysis established in parallel to these techniques. A new term is herein proposed for the field of studies aimed at the exploitation of characteristic arrays of specialized natural products of plant taxa: plant chemophenetics. Chemophenetic studies as defined here are studies aimed at describing the array of specialized secondary metabolites in a given taxon. Thus, chemophenetic studies contribute to the phenetic description of taxa, similar to anatomical, morphological, and karyological approaches, which have already been recognized as of major importance for establishing “natural” systems, and which continue to be of the utmost importance for the description of organisms classified with the help of modern molecular methods.

 

Reviews and book chapters

Scharenberg, F., Zidorn, C., 2018. Genuine and sequestered natural products from the genus Orobanche (Orobanchaceae, Lamiales). Molecules 23, 2821. doi:10.3390/molecules23112821

Epifano, F., Fiorito, S., Genovese, S., Granica, S., Vitalini, S., Zidorn, C., 2015. Phytochemistry of the genus Skimmia (Rutaceae). Phytochemistry 115, 27-43. doi:10.1016/j.phytochem.2015.02.014

Sareedenchai, V., Zidorn, C., 2010. Flavonoids as chemosystematic markers in the tribe Cichorieae of the Asteraceae. Biochem. Syst. Ecol. 38, 935-957. doi:10.1016/j.bse.2009.09.006 

Zidorn, C., 2008. Plant Chemosystematics. In: Waksmundzka-Hajnos, M., Sherma, J., Kowalska, T. (Eds.): Thin Layer Chromatography in Phytochemistry. Taylor & Francis, Boca Raton, pp. 77-101.

Zidorn, C., 2008. Sesquiterpene lactones and their precursors as chemosystematic markers in the tribe Cichorieae of the Asteraceae. Phytochemistry 69, 2270-2296. doi:10.1016/j.phytochem.2008.06.013

 

Original publications (selection)

Shulha, O., Çiçek, S.S., Wangensteen, H., Kroes, J., Mäder, M., Girreser, U., Sendker, J., Jöhrer, K., Greil, R., Schühly, W., Mangoni, A., Grauso, L., van Thriel, C., Zidorn, C., 2019., Lignans and sesquiterpene lactones from Hypochaeris radicata subsp. neapolitana (Asteraceae, Cichorieae). Phytochemistry 165, 112047. doi:10.1016/j.phytochem.2019.05.020

Enke, N., Gemeinholzer, B., Zidorn, C., 2012. Molecular and phytochemical systematics of the subtribe Hypochaeridinae (Asteraceae, Cichorieae). Org. Divers. Evol. 12, 1-16. doi:10.1007/s13127-011-0064-0

Cicek, S., Untersulzner, C., Schwaiger, S., Zidorn, C., 2012. Caffeoyl-D-glucaric acid derivatives in the genus Gnaphalium (Asteraceae: Gnaphalieae). Rec. Nat. Prod. 6, 311-315. http://www.acgpubs.org/RNP/2012/Volume%206/Issue%201/44-RNP-1102-492.pdf

Grass, S., Zidorn, C., Blattner, F.R., Stuppner, H., 2006. Comparative molecular and phytochemical investigation of Leontodon autumnalis (Asteraceae, Lactuceae) populations from Central Europe. Phytochemistry 67, 122-131. doi:10.1016/j.phytochem.2005.10.019

Zidorn, C., Sturm, S., Dawson, J.W., van Klink, J.W., Stuppner, H., Perry, N.B., 2002. Chemosystematic investigations of irregular diterpenes in Anisotome and related New Zealand Apiaceae. Phytochemistry 59, 293-304. doi: 10.1016/S0031-9422(01)00472-1

Zidorn, C., Stuppner, H., 2001. Evaluation of chemosystematic characters in the genus Leontodon. Taxon 50, 115-133. Stable URL: http://www.jstor.org/stable/1224515